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Our model predicts 11% of extreme preterm infants (< 28 weeks gestational age at birth) die prior to first hospital discharge, while 54, 23, and 12% of infants will be diagnosed with none/mild, intermediate, and severe BPD, respectively. Figure 1 shows the results of a validation exercise between our first-order simulation estimates and the CNN's 2015 reported BPD status at 36 weeks of age (including mortality) . The results show our estimates slightly over-estimate the proportion of patients with severe BPD, however all ‘real world' values fall within the 95% confidence interval of our model. Figures 2 and 3 present the simulated outcome distribution of total cost and cumulative QALYs respectively.
Full lives questioned pricing certainly one of survivors to discharge is actually $716,912 (95% CI: $416,one hundred thousand – $step one,275,000), 28% ($197,100) from which try incurred in the first year. I guess an extra 13% (ninety,600) of lives costs are obtain on 2nd year due to infirmary visits and you will hospital admissions. 3% ($9560) off total can cost you, that have a very progressive annual decrease in questioned will cost you along side patient lifestyle, symbolizing can cost you incurred of significant issue set-up over the years. (more…)